DOI: 10.22184/1993-8578.2024.17.1.26.31
The response of cells to mechanical signals plays a key role in biological processes such as organ development, tissue regeneration, aging and cancer development. Changes in mechanical properties, including stiffness and viscosity, show how cells and tissues react to stress and how their biological functions depend on it. Scanning probe microscopy (SPM) is a versatile tool for quantitative characterization of the mechanical properties of tissues and cells in vivo. Data on the mechanical properties of biological objects obtained using atomic force and capillary microscopy can be associated with biological processes and pathologies in tissues.