DOI: 10.22184/1993-8578.2021.14.6.328.333

Even with substantial sensitivity at high magnetic field, it is still challenging to investigate small-scale structures, such as brain cortex. A recent study has shown that very high resolution diffusion imaging is possible allowing investigation the cortical depth dependence of diffusion properties over the whole human brain in vivo. The results revealed that the main diffusion tensor orientation in the cortex is perpendicular to the cortical surface. At the same time the main diffusion direction is mostly tangential at banks and radial at the tips of the white matter – grey matter interface. Thus quantitative diffusion tensor measures can reveal structural organization of cells in the human cerebral cortex with the potential to characterize cortical cytoarchitecture in vivo and to investigate the pathophysiology of diseases associated with changes in cortical grey matter.


Разработка: студия Green Art