We have developed a renormalization group method in order to explore the influence of a large range of geometrical and physical microparameters on the effective diffusion coefficient. The main element of this method comprises of the renormalization of structural parameters from the micro- to the millimeter scale of the random multi-component white matter of the brain. Our approach enhances the Sen-Basser model of the brain white matter [Sen P. N., Basser P. J., Biophys. J., 89 (2005) 2927] by taking the influence of disorder into consideration and allowing quantitative investigation of the sensitivity of the effective diffusion coefficient to the variations of the dominant set of microparameters.


Разработка: студия Green Art